Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
Blog Article
one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity associated with bortezomib, a proteasome inhibitor used in the procedure of multiple myeloma. Its synthesis or study is crucial for making sure the purity and protection in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug used in the treatment method of prostate most cancers by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A critical compound during the synthesis of imatinib, a drug that targets particular forms of most cancers, like Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers which include breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their research is essential for optimizing the creation process and making certain superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is made use of to deal with breast most cancers, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the treatment of breast cancer. Different intermediates assist in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Employed in the synthesis of paclitaxel, a (7a chemotherapy drug effective in treating cancers including ovarian, breast, and lung most cancers.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the remedy of colorectal cancer and smaller mobile lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved with the synthesis of adamantane derivatives, that have a variety of apps, together with antiviral Homes.
Vildagliptin Intermediates: Utilized in the creation of vildagliptin, an oral drug for sort 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar amounts.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is involved in the synthesis of various gluconic acid derivatives, which can be used in meals, pharmaceutical, and industrial programs.
Canagliflozin 4S)-3-Hydroxy-4-phenyl-2-azetidinone Intermediate 2: A precursor in the synthesis of canagliflozin, a medication used to manage form 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).